ERP On Demand Platform - Complementary Effects Using the Example of a Sustainability Benchmarking Service

Platforms for SaaS-based enterprise applications are prospering and the number of on-demand ERP vendors is increasing. We combine both phenomena for the first time and illustrate how the integration of a sustainability benchmarking service into an on-demand ERP platform provides added value beyond pure cost savings. By applying a qualitative system dynamics approach we identify self-reinforcing mechanisms which allow a faster and more comprehensive market penetration compared to providing these services separately

Confidential Information-Sharing for Automated Sustainability Benchmarks

The pressure on enterprises to manage and improve their environmental sustainability is steadily increasing. Despite the growing awareness in the IS community and business practice, current IS solutions remain in an initial state. Sustainability benchmarking is seen as a novel and effective tool in this context. However, sustainability benchmarking faces two major obstacles: First, the heterogeneity of the data requires significant pre-processing, and, second, the sensitivity of the data causes enterprises to reluctantly share this data. Our contribution is twofold: After analyzing the data input problem and identifying appropriate and available solutions, we present a secure sustainability benchmarking service (SBS) to overcome the information-sharing problem. Our service uses homomorphic encryption to protect the data during processing and differential privacy to protect against leakages from the reports. Finally, we evaluate in detail a prototypical implementation of this secure sustainability benchmarking service and illustrate its applicability in industry

Untersuchung zur Lernkultur in Online-Kursen

Ausgehend von einer veränderten, durch Lern- und Kompetenzorientierung geprägten Lernkultur analysieren die Autorinnen zwölf mehrwöchige Online-Kurse mit insgesamt 130 Teilnehmer/innen. Die Autorinnen nehmen ein Klima der hohen Wertschätzung unter den Lernenden wahr sowie gegenseitiges Feedback in den Reflexions- und Diskussionsprozessen, welches das Lernen verstärkt. Die Hypothese, dass in rein virtuellen, mehrwöchigen Weiterbildungskursen eine veränderte Lernkultur gefördert und gelebt wird, wird mittels halbstrukturierter Interviews sowie qualitativer Inhaltsanalyse der Beiträge in den Diskussionsforen untersucht. (DIPF/ Orig.

Instances and connectors : issues for a second generation process language

This work is supported by UK EPSRC grants GR/L34433 and GR/L32699Over the past decade a variety of process languages have been defined, used and evaluated. It is now possible to consider second generation languages based on this experience. Rather than develop a second generation wish list this position paper explores two issues: instances and connectors. Instances relate to the relationship between a process model as a description and the, possibly multiple, enacting instances which are created from it. Connectors refers to the issue of concurrency control and achieving a higher level of abstraction in how parts of a model interact. We believe that these issues are key to developing systems which can effectively support business processes, and that they have not received sufficient attention within the process modelling community. Through exploring these issues we also illustrate our approach to designing a second generation process language.Postprin

Aerodynamic investigations of ventilated brake discs.

The heat dissipation and performance of a ventilated brake disc strongly depends on the aerodynamic characteristics of the flow through the rotor passages. The aim of this investigation was to provide an improved understanding of ventilated brake rotor flow phenomena, with a view to improving heat dissipation, as well as providing a measurement data set for validation of computational fluid dynamics methods. The flow fields at the exit of four different brake rotor geometries, rotated in free air, were measured using a five-hole pressure probe and a hot-wire anemometry system. The principal measurements were taken using two-component hot-wire techniques and were used to determine mean and unsteady flow characteristics at the exit of the brake rotors. Using phase-locked data processing, it was possible to reveal the spatial and temporal flow variation within individual rotor passages. The effects of disc geometry and rotational speed on the mean flow, passage turbulence intensity, and mass flow were determined. The rotor exit jet and wake flow were clearly observed as characterized by the passage geometry as well as definite regions of high and low turbulence. The aerodynamic flow characteristics were found to be reasonably independent of rotational speed but highly dependent upon rotor geometry

Chemically-synthesised, atomically-precise gold clusters deposited and activated on titania

Synchrotron XPS was used to investigate a series of chemically-synthesised, atomically-precise gold clusters Au(n)(PPh₃)(y) (n = 8, 9, 11 and 101, with y depending on cluster size) immobilized on titania nanoparticles. The gold clusters were washed with toluene at 100 °C or calcined at 200 °C to remove the organic ligand. From the position of the Au 4f₇/₂ peak it is concluded that cluster size is not altered through the deposition. From the analysis of the phosphorous spectra, it can be concluded that the applied heat treatment removes the organic ligands. Washing and calcination leads to partial oxidation and partial agglomeration of the clusters. Oxidation of the clusters is most likely due to the interaction of the cluster core with the oxygen of the titania surface after removal of ligands. The position of the Au 4f₇/₂ peak indicates that the size of the agglomerated clusters is still smaller than that of Au₁₀₁.David P. Anderson, Jason F. Alvino, Alexander Gentleman, Hassan Al Qahtani, Lars Thomsen, Matthew I. J. Polson, Gregory F. Metha, Vladimir B. Golovko and Gunther G. Andersso

Whole-Genome Sequencing of a Single Proband Together with Linkage Analysis Identifies a Mendelian Disease Gene

Although more than 2,400 genes have been shown to contain variants that cause Mendelian disease, there are still several thousand such diseases yet to be molecularly defined. The ability of new whole-genome sequencing technologies to rapidly indentify most of the genetic variants in any given genome opens an exciting opportunity to identify these disease genes. Here we sequenced the whole genome of a single patient with the dominant Mendelian disease, metachondromatosis (OMIM 156250), and used partial linkage data from her small family to focus our search for the responsible variant. In the proband, we identified an 11 bp deletion in exon four of PTPN11, which alters frame, results in premature translation termination, and co-segregates with the phenotype. In a second metachondromatosis family, we confirmed our result by identifying a nonsense mutation in exon 4 of PTPN11 that also co-segregates with the phenotype. Sequencing PTPN11 exon 4 in 469 controls showed no such protein truncating variants, supporting the pathogenicity of these two mutations. This combination of a new technology and a classical genetic approach provides a powerful strategy to discover the genes responsible for unexplained Mendelian disorders